Human Ras-related protein Rab-40A (RAB40A) ELISA Kit

Product specifications

ELISA Kits

Ras-related protein Rab-40A (RAB40A)

Human

Colorimetric

Quantitative

0.156 ng/ml - 10 ng/ml

Optimal dilutions/concentrations should be determined by the end user.

96 tests

Lyophilized

ELISA

Tissue homogenates, cell lysates and other biological fluids.

Shipped within 5-15 working days. The validity for this kit is 6 months.

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

No

Q8WXH6

RAR2,RAR2A,SOCS box-containing protein RAR2A,Protein Rar-2,Ras-related protein Rab-40A

Elisa kits for RAB40A

RUO

Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

RAB40A, member RAS oncogene family (RAB40A) is a member of the RAB GTPase family and plays a significant role in regulating vesicular trafficking, particularly in the context of endosomal and lysosomal systems. It participates in sorting and trafficking vesicles from the Golgi complex to their appropriate destinations within the cell. RAB40A is also involved in the regulation of receptor trafficking and recycling, ensuring that cellular receptors are properly transported to and from the plasma membrane. This function is critical for maintaining receptor sensitivity, cellular signaling, and membrane homeostasis. In addition to its role in intracellular trafficking, RAB40A has been implicated in the regulation of autophagy, a cellular process that helps remove damaged proteins and organelles, promoting cell survival and homeostasis. Dysfunction of RAB40A can lead to disruptions in receptor recycling, which has been linked to various diseases, including cancers, where aberrant receptor signaling supports tumor growth. Additionally, its role in autophagy links RAB40A to the pathogenesis of neurodegenerative diseases, where impaired protein clearance leads to cellular dysfunction and neuronal death.

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