Human Ras-related protein Rab-12 (RAB12) ELISA Kit

Product specifications

ELISA Kits

Ras-related protein Rab-12 (RAB12)

Human

Colorimetric

Quantitative

0.156 ng/ml - 10 ng/ml

< 0.06 ng/ml

Optimal dilutions/concentrations should be determined by the end user.

96 tests

Lyophilized

ELISA

Tissue homogenates, cell lysates and other biological fluids.

Shipped within 5-15 working days. The validity for this kit is 6 months.

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

No

Q6IQ22

616448

Ras-related protein Rab-12

Elisa kits for RAB12

RUO

Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

RAB12, member RAS oncogene family (RAB12) is a member of the small GTPase family and plays a crucial role in regulating vesicular trafficking and membrane dynamics RAB12 is involved in the regulation of autophagy, the process by which cells degrade and recycle damaged organelles and proteins It also contributes to the movement of late endosomes and lysosomes, ensuring proper intracellular sorting and degradation of cellular waste materials RAB12 plays a role in the trafficking of proteins between cellular compartments, especially in regulating the transport of key receptors, and is essential for maintaining cellular homeostasis Additionally, RAB12 has been shown to participate in regulating cell migration and adhesion, as its dysfunction can lead to defects in receptor recycling and membrane protein turnover RAB12’s role in vesicle trafficking and autophagy links it to neurodegenerative diseases, where impaired protein degradation and clearance lead to cellular dysfunction It is also involved in cancer biology, where altered vesicular trafficking can contribute to tumor progression, metastasis, and chemotherapy resistance

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