Human Ragulator complex protein LAMTOR4 (LAMTOR4) ELISA Kit

Name: Human Ragulator complex protein LAMTOR4 (LAMTOR4) ELISA Kit
Brand: Abbexa
SKU: abx531706
Price: 715 EUR
Availability: OnlineOnly

Este producto es parte de Ragulator complex protein LAMTOR

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for LAMTOR4

proveedor

Abbexa

reference

abx531706

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Ragulator complex protein LAMTOR4 (LAMTOR4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Ragulator complex protein LAMTOR4 (LAMTOR4) concentrations in tissue homogenates, cell lysates and other biological fluids.

Background

Ragulator complex protein LAMTOR4 is an essential component of the Ragulator complex that interacts with Rag GTPases on the lysosomal membrane to activate mTORC1 signaling in response to amino acid availability LAMTOR4 functions as a scaffold within the complex, enabling mTORC1 to sense nutrient sufficiency and regulate anabolic and catabolic processes such as protein synthesis, autophagy, and cellular metabolism Loss of LAMTOR4 disrupts mTORC1 activation, leading to impaired cell growth, energy metabolism, and lysosomal function Studies indicate that LAMTOR4 is critical for immune cell activation, particularly in T-cell and macrophage responses, where mTOR signaling governs cellular proliferation and differentiation Dysregulation of LAMTOR4 has been linked to neurodegenerative diseases, cancers, and metabolic disorders, as impaired lysosome-mTORC1 communication disrupts cellular homeostasis and stress responses Its role in lysosomal positioning and signaling highlights its importance as a central regulator of nutrient sensing and cellular growth pathways

Características del producto

immunogen target

Ragulator complex protein LAMTOR4 (LAMTOR4)

reactivity

Human

test range

0.156 ng/ml - 10 ng/ml

assay data

Quantitative

form

Lyophilized

detection method

Colorimetric

sample type

Tissue homogenates, cell lysates and other biological fluids.

size 1

96 tests

alias

C7orf59,late endosomal/lysosomal adaptor, MAPK and MTOR activator 4

storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

or code

LAMTOR4

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/Q0VGL1

gene id

https://www.ncbi.nlm.nih.gov/gene/389541

note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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proveedor

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reference

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Tested Applications

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status

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Human LAMTOR4 Protein

proveedor

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reference

abx263435

Tested Applications

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status

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LAMTOR4 is a recombinant protein.

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