Human Ragulator Complex Protein LAMTOR3 / MAPKSP1 (LAMTOR3) ELISA Kit

Este producto es parte de Ragulator complex protein LAMTOR
Human Ragulator Complex Protein LAMTOR3 / MAPKSP1 (LAMTOR3) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for LAMTOR3

proveedor

Abbexa

reference

abx392238

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Ragulator complex protein LAMTOR3 (LAMTOR3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Ragulator complex protein LAMTOR3 (LAMTOR3) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Ragulator complex protein LAMTOR3 is an integral subunit of the lysosomal Ragulator complex that functions as a critical activator of the mTORC1 pathway in response to amino acid and nutrient signaling LAMTOR3 is required for the localization of Rag GTPases to the lysosomal surface, which facilitates the recruitment of mTORC1 and its activation upon nutrient availability Beyond its role in nutrient sensing, LAMTOR3 regulates lysosomal positioning and intracellular trafficking processes Dysregulation of LAMTOR3 disrupts mTOR signaling and has been linked to cellular growth defects, metabolic disorders, and tumor progression Studies highlight its role in maintaining energy balance and cell survival under stress conditions LAMTOR3 also participates in immune cell responses, as mTORC1 signaling is vital for T-cell activation and differentiation Its involvement in nutrient sensing and cellular homeostasis underscores its importance in both normal physiology and disease pathogenesis

Características del producto

category

ELISA Kits


immunogen target

Ragulator Complex Protein LAMTOR3 / MAPKSP1 (LAMTOR3)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.094 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

MAP2K1IP1,MAPBP,MAPKSP1,MP1,PRO0633,Ragulator3,Mitogen-activated protein kinase scaffold protein 1,late endosomal/lysosomal adaptor, MAPK and MTOR activator 3


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

LAMTOR3


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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reference

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reactivity

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