anti- MAPKSP1 antibody

Product specifications

Primary Antibodies

MAPK scaffold protein 1

Rabbit

human,mouse,rat

WB: 1:500-1:2000; IHC: 1:20-1:200

polyclonal

Unconjugated

IgG

14 kDa

≥95% as determined by SDS-PAGE

Immunogen affinity purified

100µg

liquid

ELISA, WB, IHC

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Q9UHA4

MAP2K1IP1,MAPBP,MAPKSP1,MP1,PRO0633,Ragulator3,Mitogen-activated protein kinase scaffold protein 1,late endosomal/lysosomal adaptor, MAPK and MTOR activator 3

Antibody anti-LAMTOR3

RUO

This product is for research use only.

Ragulator complex protein LAMTOR3 is an integral subunit of the lysosomal Ragulator complex that functions as a critical activator of the mTORC1 pathway in response to amino acid and nutrient signaling LAMTOR3 is required for the localization of Rag GTPases to the lysosomal surface, which facilitates the recruitment of mTORC1 and its activation upon nutrient availability Beyond its role in nutrient sensing, LAMTOR3 regulates lysosomal positioning and intracellular trafficking processes Dysregulation of LAMTOR3 disrupts mTOR signaling and has been linked to cellular growth defects, metabolic disorders, and tumor progression Studies highlight its role in maintaining energy balance and cell survival under stress conditions LAMTOR3 also participates in immune cell responses, as mTORC1 signaling is vital for T-cell activation and differentiation Its involvement in nutrient sensing and cellular homeostasis underscores its importance in both normal physiology and disease pathogenesis

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