Human Ragulator complex protein LAMTOR1 (LAMTOR1) ELISA Kit
715€ (96 tests)
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name
Human Ragulator complex protein LAMTOR1 (LAMTOR1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx257279
tested applications
ELISA
Description
Human Ragulator complex protein LAMTOR1 (LAMTOR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human LAMTOR1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Ragulator complex protein LAMTOR1 (LAMTOR1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.188 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q6IAA8 |
| Alias | p18,PDRO,C11orf59,p27RF-Rho,Ragulator1,Lipid raft adaptor protein p18,late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 |
| Background | Elisa kits for LAMTOR1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Ragulator complex protein LAMTOR1 is a core component of the Ragulator complex, which anchors Rag GTPases to the lysosomal membrane, functioning as a key regulator of mTORC1 signaling LAMTOR1 is essential for nutrient sensing and the activation of mTORC1, a central signaling hub that regulates cellular metabolism, growth, and autophagy in response to amino acid availability It interacts with other components of the Ragulator complex to facilitate lysosome-localized mTORC1 activation, ensuring proper coordination of anabolic and catabolic processes Dysregulation of LAMTOR1 impairs mTORC1 signaling, contributing to metabolic disorders, cancer progression, and neurodegenerative diseases where nutrient sensing and autophagic balance are disrupted LAMTOR1 is also involved in lysosomal positioning and function, highlighting its role in cellular homeostasis and stress responses Recent studies have demonstrated its involvement in immune cell activation and pathogen response, further emphasizing its critical function as a central regulator of lysosome-mTORC1 signaling and cellular metabolism
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