Human RAB37, Member RAS Oncogene Family (RAB37) Protein
234€ (10 µg)
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935106861
info@markelab.com
name
Human RAB37, Member RAS Oncogene Family (RAB37) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168195
tested applications
WB, SDS-PAGE
Description
RAB37, Member RAS Oncogene Family Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | RAB37, Member RAS Oncogene Family (RAB37) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 26.4 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser19-Cys220 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96AX2 |
| Alias | Ras-related protein Rab-37 |
| Background | Protein RAB37 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
RAB37, member RAS oncogene family (RAB37) is a small GTPase involved in intracellular vesicular trafficking, particularly in the regulation of endocytosis and exocytosis RAB37 plays a crucial role in the sorting and recycling of proteins between different cellular compartments, ensuring that membrane-bound proteins, lipids, and other cargo are correctly processed and directed to their destinations This function is essential for maintaining cellular homeostasis, signal transduction, and membrane dynamics Additionally, RAB37 has been shown to play a role in autophagy, the process of degrading and recycling damaged or unnecessary cellular components to maintain cellular health Its dysfunction can contribute to several pathologies, including cancer and neurodegenerative diseases, where impaired vesicular trafficking leads to dysregulated cellular signaling and protein accumulation, contributing to disease progression
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