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Human P2Y Purinoceptor 6 (P2RY6) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits P2RY6
proveedor
Abbexareference
abx382015Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Purinergic Receptor P2Y, G Protein Coupled 6 (P2RY6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human P2RY6 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
P2RY6 is a G protein-coupled receptor activated by extracellular UDP (uridine diphosphate) and to a lesser extent UTP, mediating cellular responses to nucleotide release during tissue injury or inflammation. P2RY6 couples primarily to Gq proteins, leading to phospholipase C (PLC) activation, calcium mobilization, and downstream signaling that regulates inflammation, immune responses, and smooth muscle contraction. P2RY6 is widely expressed in immune cells, smooth muscle, and epithelial tissues, where it modulates cytokine production, chemotaxis, and vascular tone. In inflammation, P2RY6 plays a central role in recruiting immune cells and amplifying inflammatory signaling, contributing to diseases such as asthma, arthritis, and colitis. It is also involved in smooth muscle contraction in the vascular and gastrointestinal systems. Dysregulation of P2RY6 signaling is linked to chronic inflammatory diseases, cardiovascular dysfunction, and metabolic disorders. P2RY6 antagonists are being investigated as therapeutic agents for inflammation, asthma, and vascular diseases due to their role in regulating immune and smooth muscle responses.
Características del producto
category
ELISA Kits
immunogen target
P2Y Purinoceptor 6 (P2RY6)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.07 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
P2RY6,uridine nucleotide receptor,P2Y6,P2Y ATP receptor 6,P2Y purinoceptor 6,pyrimidinergic receptor P2Y
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
P2RY6
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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