Human P2Y Purinoceptor 6 (P2RY6) ELISA Kit

Este producto es parte de P2RY  - Purinergic Receptor P2Y
Human P2Y Purinoceptor 6 (P2RY6) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for P2RY6

proveedor

Abbexa

reference

abx382015

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human P2Y Purinoceptor 6 (P2RY6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human P2RY6 concentrations.


Background

P2RY6 is a G protein-coupled receptor activated by extracellular UDP (uridine diphosphate) and to a lesser extent UTP, mediating cellular responses to nucleotide release during tissue injury or inflammation. P2RY6 couples primarily to Gq proteins, leading to phospholipase C (PLC) activation, calcium mobilization, and downstream signaling that regulates inflammation, immune responses, and smooth muscle contraction. P2RY6 is widely expressed in immune cells, smooth muscle, and epithelial tissues, where it modulates cytokine production, chemotaxis, and vascular tone. In inflammation, P2RY6 plays a central role in recruiting immune cells and amplifying inflammatory signaling, contributing to diseases such as asthma, arthritis, and colitis. It is also involved in smooth muscle contraction in the vascular and gastrointestinal systems. Dysregulation of P2RY6 signaling is linked to chronic inflammatory diseases, cardiovascular dysfunction, and metabolic disorders. P2RY6 antagonists are being investigated as therapeutic agents for inflammation, asthma, and vascular diseases due to their role in regulating immune and smooth muscle responses.

Características del producto

category

ELISA Kits


immunogen target

P2Y Purinoceptor 6 (P2RY6)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.07 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

P2RY6,uridine nucleotide receptor,P2Y6,P2Y ATP receptor 6,P2Y purinoceptor 6,pyrimidinergic receptor P2Y


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

P2RY6


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

Human P2RY6 (P2Y purinoceptor 6 ) ELISA Kit

Human P2RY6 (P2Y purinoceptor 6 ) ELISA Kit

proveedor

FineTest

reference

EH10834

reactivity

human

status

RUO

Precio a consultar

Ver más

anti- P2RY6 antibody

anti- P2RY6 antibody

proveedor

FineTest

reference

FNab06074

Tested Applications

ELISA, WB

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a pho...

Precio a consultar

Ver más

P2Y Purinoceptor 6 (P2RY6) Antibody

P2Y Purinoceptor 6 (P2RY6) Antibody

proveedor

Abbexa

reference

abx001929

Tested Applications

ELISA, WB

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

P2Y Purinoceptor 6 (P2RY6) Antibody is a Rabbit Polyclonal antibody against P2RY6. The product of this gene belongs to t...

195€ (20 µl)

Ver más