Human P2Y Purinoceptor 6 (P2RY6) ELISA Kit

Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for P2RY6
proveedor
Abbexareference
abx382015Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human P2Y Purinoceptor 6 (P2RY6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human P2RY6 concentrations.
Background
P2RY6 is a G protein-coupled receptor activated by extracellular UDP (uridine diphosphate) and to a lesser extent UTP, mediating cellular responses to nucleotide release during tissue injury or inflammation. P2RY6 couples primarily to Gq proteins, leading to phospholipase C (PLC) activation, calcium mobilization, and downstream signaling that regulates inflammation, immune responses, and smooth muscle contraction. P2RY6 is widely expressed in immune cells, smooth muscle, and epithelial tissues, where it modulates cytokine production, chemotaxis, and vascular tone. In inflammation, P2RY6 plays a central role in recruiting immune cells and amplifying inflammatory signaling, contributing to diseases such as asthma, arthritis, and colitis. It is also involved in smooth muscle contraction in the vascular and gastrointestinal systems. Dysregulation of P2RY6 signaling is linked to chronic inflammatory diseases, cardiovascular dysfunction, and metabolic disorders. P2RY6 antagonists are being investigated as therapeutic agents for inflammation, asthma, and vascular diseases due to their role in regulating immune and smooth muscle responses.
Características del producto
category
ELISA Kits
immunogen target
P2Y Purinoceptor 6 (P2RY6)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.07 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
P2RY6,uridine nucleotide receptor,P2Y6,P2Y ATP receptor 6,P2Y purinoceptor 6,pyrimidinergic receptor P2Y
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
P2RY6
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
Human P2RY6 (P2Y purinoceptor 6 ) ELISA Kit

proveedor
FineTestreference
EH10834reactivity
humanstatus
RUOPrecio a consultar
Ver másanti- P2RY6 antibody

proveedor
FineTestreference
FNab06074Tested Applications
ELISA, WBreactivity
human,mouse,ratstatus
RUOclonality
polyclonalReceptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a pho...
Precio a consultar
Ver másP2Y Purinoceptor 6 (P2RY6) Antibody

proveedor
Abbexareference
abx001929Tested Applications
ELISA, WBreactivity
Human, Mousestatus
RUOclonality
PolyclonalP2Y Purinoceptor 6 (P2RY6) Antibody is a Rabbit Polyclonal antibody against P2RY6. The product of this gene belongs to t...
195€ (20 µl)
Ver más