Human P2Y Purinoceptor 13 (P2RY14) ELISA Kit
715€ (96 tests)
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935106861
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name
Human P2Y Purinoceptor 13 (P2RY14) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx152614
tested applications
ELISA
Description
Human Purinergic Receptor P2Y, G Protein Coupled 14 (P2RY14) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Purinergic Receptor P2Y, G Protein Coupled 14 (P2RY14) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Purinergic Receptor P2Y, G Protein Coupled 14 (P2RY14)
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | P2Y Purinoceptor 13 (P2RY14) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | P2RY14,G protein coupled receptor for UDP-glucose,G protein-coupled receptor 105,GPR105,P2Y purinoceptor 14,G-protein coupled receptor 105,purinergic receptor P2Y,BPR105,P2Y14 |
| Background | Elisa kits for P2RY14 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
P2RY14 is a G protein-coupled receptor activated by UDP-sugars, such as UDP-glucose and UDP-galactose. P2RY14 primarily couples to Gi/o proteins, inhibiting adenylate cyclase, reducing cAMP levels, and modulating inflammatory and immune responses. P2RY14 is widely expressed in immune cells, including neutrophils, macrophages, and lymphocytes, as well as in the gastrointestinal tract and central nervous system. It plays a critical role in innate immunity by mediating chemotaxis, cytokine production, and immune cell recruitment during inflammation and infection. In the gastrointestinal system, P2RY14 is involved in mucus production and epithelial repair. Dysregulation of P2RY14 is associated with inflammatory diseases, immune dysfunction, and metabolic disorders. P2RY14 is emerging as a therapeutic target for conditions like asthma, diabetes, and gastrointestinal inflammation, where modulation of UDP-sugar signaling can improve immune regulation and tissue homeostasis.
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