Human PTPRJ (Protein Tyrosine Phosphatase Receptor Type J) ELISA Kit

Este producto es parte de PTPR - protein tyrosine phosphatase receptor type
Human PTPRJ (Protein Tyrosine Phosphatase Receptor Type J) ELISA Kit
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Name
Human PTPRJ (Protein Tyrosine Phosphatase Receptor Type J) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH3683
Tested Applications
ELISA

Documentos del producto

Instrucciones
Descargar
Data sheet

Especificaciones del producto

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.313-20ng/ml
Sensitivity
0.188ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
Q12913
Alias
DEP1,SCC1,CD148,THC10,HPTPeta,R-PTP-J,HPTP eta,R-PTP-ETA,Protein-tyrosine phosphatase receptor type J,Density-enhanced phosphatase 1,Protein-tyrosine phosphatase eta,Receptor-type tyrosine-protein phosphatase eta
Background
Elisa kits for PTPRJ
Status
RUO

Background

Protein tyrosine phosphatase receptor type J (PTPRJ) is a transmembrane protein belonging to the protein tyrosine phosphatase family, which regulates cellular signaling pathways by dephosphorylating tyrosine residues on target proteins this receptor-like phosphatase is broadly expressed in various tissues including endothelial cells, immune cells, and epithelial cells and is implicated in controlling cell growth, adhesion, and migration it negatively regulates key signaling pathways such as those mediated by receptor tyrosine kinases including VEGFR, PDGFR, and EGFR, making it a critical player in angiogenesis, immune responses, and tumor suppression its reduced expression or functional inactivation has been associated with several cancers, including colorectal, thyroid, and breast cancers, where its loss promotes tumor progression and metastasis emerging studies suggest its role in modulating the immune microenvironment and its potential as a therapeutic target to enhance immune checkpoint therapies ongoing research focuses on elucidating its broader functions in cellular homeostasis and its utility in precision medicine.

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