Human Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) CLIA Kit

Este producto es parte de PTPR - protein tyrosine phosphatase receptor type
Human Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) CLIA Kit
845€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
Human Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) CLIA Kit
Category
CLIA Kits
Provider
Abbexa
Reference
abx492857
Tested Applications
CLIA

Description

Human Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
CLIA Kits
Immunogen Target
Protein Tyrosine Phosphatase Receptor Type J (PTPRJ)
Reactivity
Human
Detection Method
Chemiluminescent
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.312 ng/ml - 20 ng/ml
Sensitivity
< 0.117 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard: Lyophilized
Tested Applications
CLIA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-20 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
DEP1,SCC1,CD148,THC10,HPTPeta,R-PTP-J,HPTP eta,R-PTP-ETA,Protein-tyrosine phosphatase receptor type J,Density-enhanced phosphatase 1,Protein-tyrosine phosphatase eta,Receptor-type tyrosine-protein phosphatase eta
Background
CLIA Kits PTPRJ
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES.  The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.  Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

Protein tyrosine phosphatase receptor type J (PTPRJ) is a transmembrane protein belonging to the protein tyrosine phosphatase family, which regulates cellular signaling pathways by dephosphorylating tyrosine residues on target proteins this receptor-like phosphatase is broadly expressed in various tissues including endothelial cells, immune cells, and epithelial cells and is implicated in controlling cell growth, adhesion, and migration it negatively regulates key signaling pathways such as those mediated by receptor tyrosine kinases including VEGFR, PDGFR, and EGFR, making it a critical player in angiogenesis, immune responses, and tumor suppression its reduced expression or functional inactivation has been associated with several cancers, including colorectal, thyroid, and breast cancers, where its loss promotes tumor progression and metastasis emerging studies suggest its role in modulating the immune microenvironment and its potential as a therapeutic target to enhance immune checkpoint therapies ongoing research focuses on elucidating its broader functions in cellular homeostasis and its utility in precision medicine.

Productos relacionados

abx068775

Human Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) Protein

Human Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) is a recombinant Human protein expressed in E. coli.…

Ver producto
abx104380

Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) Antibody

Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type J (PTPRJ).…

Ver producto
abx114881

Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) Antibody

Protein Tyrosine Phosphatase, Receptor Type, J Antibody is a Rabbit Polyclonal antibody against Protein Tyrosine Phospha…

Ver producto