Human Protein Tyrosine Phosphatase Receptor Type A (PTPRA) Protein

Este producto es parte de PTPR - protein tyrosine phosphatase receptor type
Human Protein Tyrosine Phosphatase Receptor Type A (PTPRA) Protein

Pida mas información

935106861

info@markelab.com

Precio

208€ (10 µg)

Protein PTPRA

proveedor

Abbexa

reference

abx650359

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human PTPRA Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).


Background

PTPRA is a receptor-like protein tyrosine phosphatase involved in dephosphorylating tyrosine residues in target proteins to regulate cellular signaling pathways. Structurally, it has an extracellular domain, a transmembrane region, and two intracellular phosphatase domains, with the first domain being enzymatically active. PTPRA is expressed ubiquitously, with high levels in brain and muscle tissues. It activates Src family kinases by dephosphorylating inhibitory phosphotyrosines, influencing cell proliferation, adhesion, and migration. PTPRA plays significant roles in neuronal signaling, integrin-mediated cell adhesion, and oncogenic processes. Dysregulation is associated with cancers and neurological disorders.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Protein Tyrosine Phosphatase Receptor Type A (PTPRA)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 23.8 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Trp624-Asn800 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

PTPRA


dry ice

No


availability

Shipped within 5-7 working days.


alias

LRP,HLPR,PTPA,HEPTP,HPTPA,RPTPA,PTPRL2,HPTPalpha,R-PTP-alpha,Protein-tyrosine phosphatase alpha,Receptor-type tyrosine-protein phosphatase alpha


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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reference

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reactivity

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status

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clonality

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