Human Protein TMED8 (TMED8) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Protein TMED8 (TMED8) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx550427
tested applications
ELISA
Description
Human Protein TMED8 ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Protein TMED8 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Protein TMED8 (TMED8) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | FAM15B, L10 |
| Background | Elisa kits for TMED8 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
TMED8 is a member of the p24 family that regulates cargo trafficking and quality control within the secretory pathway, facilitating transport between the ER, ER-Golgi intermediate compartment, and Golgi apparatus. TMED8 plays an essential role in sorting and packaging cargo proteins into COPII vesicles, ensuring their efficient delivery to downstream compartments, while also mediating retrograde COPI-dependent retrieval of proteins back to the ER. TMED8 has additional roles in modulating growth factor signaling, membrane protein localization, and Golgi organization. It is expressed in a variety of tissues, particularly in rapidly proliferating cells, where it supports protein maturation, receptor signaling, and organelle homeostasis. Dysregulation of TMED8 has been associated with developmental abnormalities, cancers, and immune dysfunction due to impaired protein transport dynamics. Functional studies reveal defects in secretory pathway organization, accumulation of misfolded proteins, and disrupted signaling pathways, emphasizing its role in vesicle transport, protein quality control, and intracellular signaling.
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