Human Protein phosphatase 1 regulatory subunit 42 (PPP1R42) ELISA Kit

Este producto es parte de LRRC - Leucine-rich repeat-containing protein
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Protein phosphatase 1 regulatory subunit 42 (PPP1R42) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx539868
tested applications
ELISA

Description

Human Protein phosphatase 1 regulatory subunit 42 (PPP1R42) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Protein phosphatase 1 regulatory subunit 42 (PPP1R42) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Protein phosphatase 1 regulatory subunit 42 (PPP1R42)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q7Z4L9
OMIM
617720
Alias
LRRC67,Protein phosphatase 1 regulatory subunit 42
Background
Elisa kits for PPP1R42
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

PPP1R42 is a regulatory subunit of protein phosphatase 1 (PP1), which modulates the catalytic activity of PP1 by targeting it to specific substrates, cellular compartments, or signaling pathways. PPP1R42 is involved in processes such as centrosome function, spindle dynamics, and cell division through its interaction with microtubule-associated proteins and centrosomal components. It regulates PP1 activity to control mitotic progression, ensuring proper chromosome segregation and cell cycle regulation. PPP1R42 is predominantly expressed in tissues undergoing high rates of cell division, such as germ cells and embryonic tissues. Dysregulation of PPP1R42 leads to centrosomal defects, abnormal spindle formation, and impaired cell division, contributing to chromosomal instability and cancer progression. Functional studies indicate that PPP1R42 is essential for maintaining centrosome integrity and coordinating PP1 activity with mitotic processes to ensure accurate cell division and genomic stability.
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Ver Producto