Human Protein CBFA2T3 (CBFA2T3) ELISA Kit

Este producto es parte de CBFA2T - CBFA2/RUNX1 partner transcriptional co-repressor
Human Protein CBFA2T3 (CBFA2T3) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for CBFA2T3

proveedor

Abbexa

reference

abx386307

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Protein CBFA2T3 (CBFA2T3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Core Binding Factor Alpha Subunit 2 Translocated To 3 (CBFa2T3) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

CBFA2/RUNX1 partner transcriptional co-repressor 3 (CBFA2T3) is another member of the CBFA2T family, acting as a co-repressor in the context of RUNX1-mediated transcription CBFA2T3 works similarly to CBFA2T2 by interacting with RUNX1 to repress gene expression, thereby playing a vital role in regulating hematopoietic development and function Like its counterpart, CBFA2T3 contributes to the maintenance of normal blood cell development by modulating gene expression that is essential for stem cell differentiation and lineage commitment It helps control processes like cell proliferation, differentiation, and apoptosis during hematopoiesis Mutations or alterations in CBFA2T3 expression can lead to hematologic disorders such as leukemia, where dysfunctional co-repression can disrupt the balance of cell growth and differentiation Understanding the role of CBFA2T3 in hematopoiesis could provide valuable insights into therapeutic strategies for blood cancers and other disorders related to abnormal gene regulation

Características del producto

category

ELISA Kits


immunogen target

Protein CBFA2T3 (CBFA2T3)


reactivity

Human


test range

0.313 ng/ml - 20 ng/ml


sensitivity

< 0.19 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

ETO2,MTG16,MTGR2,ZMYND4,RUNX1T3,Zinc finger MYND domain-containing protein 4,Myeloid translocation gene on chromosome 16 protein


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

CBFA2T3


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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