Human Protein CBFA2T3 (CBFA2T3) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for CBFA2T3
proveedor
Abbexareference
abx386307Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Protein CBFA2T3 (CBFA2T3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Core Binding Factor Alpha Subunit 2 Translocated To 3 (CBFa2T3) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
CBFA2/RUNX1 partner transcriptional co-repressor 3 (CBFA2T3) is another member of the CBFA2T family, acting as a co-repressor in the context of RUNX1-mediated transcription CBFA2T3 works similarly to CBFA2T2 by interacting with RUNX1 to repress gene expression, thereby playing a vital role in regulating hematopoietic development and function Like its counterpart, CBFA2T3 contributes to the maintenance of normal blood cell development by modulating gene expression that is essential for stem cell differentiation and lineage commitment It helps control processes like cell proliferation, differentiation, and apoptosis during hematopoiesis Mutations or alterations in CBFA2T3 expression can lead to hematologic disorders such as leukemia, where dysfunctional co-repression can disrupt the balance of cell growth and differentiation Understanding the role of CBFA2T3 in hematopoiesis could provide valuable insights into therapeutic strategies for blood cancers and other disorders related to abnormal gene regulation
Características del producto
category
ELISA Kits
immunogen target
Protein CBFA2T3 (CBFA2T3)
reactivity
Human
test range
0.313 ng/ml - 20 ng/ml
sensitivity
< 0.19 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
ETO2,MTG16,MTGR2,ZMYND4,RUNX1T3,Zinc finger MYND domain-containing protein 4,Myeloid translocation gene on chromosome 16 protein
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CBFA2T3
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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