Human Protein ABHD4 (ABHD4) Protein
611€ (20 µg)
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name
Human Protein ABHD4 (ABHD4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx693289
tested applications
SDS-PAGE
Description
Human ABHD4 Protein is a recombinant protein from Human produced in Baculovirus-Insect Cells. A DNA sequence encoding the full length of human ABHD4 (NP_071343.2) (Met 1-Asp 342) was expressed, with a polyhistidine tag at the N-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | ABHD4 |
| Host | Insect |
| Origin | Human |
| Observed MW | Molecular Weight: 41 kDa Sequence Fragment: Met1-Asp342 Tag: N-terminal His tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 82% (SDS-PAGE) |
| Size 1 | 20 µg |
| Size 2 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NP_071343.2 |
| Alias | ABH4 |
| Background | Protein ABHD4 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ABHD4 is a serine hydrolase involved in lipid metabolism, particularly in the synthesis and degradation of bioactive lipids such as N-acyl phosphatidylethanolamines (NAPEs). These lipids are precursors to endocannabinoids like anandamide, which regulate processes such as pain, mood, and appetite. ABHD4 is expressed in various tissues, including the brain, where it contributes to the regulation of endocannabinoid signaling and synaptic activity. It also plays a role in phospholipid remodeling, influencing membrane dynamics and lipid signaling pathways. Dysregulation of ABHD4 has been associated with altered lipid signaling and may contribute to neurodegenerative diseases and metabolic disorders. Its enzymatic activity and structural specificity highlight its importance in maintaining lipid homeostasis and signaling, making it a potential target for therapeutic intervention in conditions involving lipid dysregulation.
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