Abhydrolase Domain Containing 4 (ABHD4) Antibody

221€ (50 µg)
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935106861
info@markelab.com
name
Abhydrolase Domain Containing 4 (ABHD4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx325187
tested applications
ELISA, IHC
Description
ABHD4 Antibody is a Rabbit Polyclonal against ABHD4.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Abhydrolase Domain Containing 4 (ABHD4) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | ELISA: 1/20000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 50 µg |
Size 2 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, IHC |
Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q8TB40 |
Gene ID | 63874 |
Alias | ABH4 |
Background | Antibody anti-ABHD4 |
Status | RUO |
Descripción
ABHD4 is a serine hydrolase involved in lipid metabolism, particularly in the synthesis and degradation of bioactive lipids such as N-acyl phosphatidylethanolamines (NAPEs). These lipids are precursors to endocannabinoids like anandamide, which regulate processes such as pain, mood, and appetite. ABHD4 is expressed in various tissues, including the brain, where it contributes to the regulation of endocannabinoid signaling and synaptic activity. It also plays a role in phospholipid remodeling, influencing membrane dynamics and lipid signaling pathways. Dysregulation of ABHD4 has been associated with altered lipid signaling and may contribute to neurodegenerative diseases and metabolic disorders. Its enzymatic activity and structural specificity highlight its importance in maintaining lipid homeostasis and signaling, making it a potential target for therapeutic intervention in conditions involving lipid dysregulation.
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