Human Prostaglandin F2 Receptor Negative Regulator (PTGFRN) Protein
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935106861
info@markelab.com
Precio
221€ (10 µg)
Protein PTGFRN
proveedor
Abbexareference
abx168748Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Human PTGFRN Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Background
Prostaglandin F2 receptor inhibitor (PTGFRN), also known as CD315 or FPRP (Fas-associated protein response-related protein), is a transmembrane protein associated with prostaglandin receptor signaling. PTGFRN is known primarily for its ability to modulate prostaglandin F2 alpha (PGF2α) receptor function, thereby impacting prostaglandin signaling pathways involved in inflammatory responses, immune modulation, and reproductive processes. PTGFRN doesn’t directly bind prostaglandins but instead influences PGF2α receptor function indirectly, regulating cellular responses to prostaglandins by modifying receptor sensitivity and availability on the cell surface. PTGFRN has a wide tissue distribution and is expressed in cells of the immune system, cardiovascular tissues, reproductive organs, and certain epithelial tissues. Its role extends beyond prostaglandin modulation, as it’s also involved in various cellular processes including cell adhesion, migration, and interactions with other membrane proteins, such as tetraspanins. PTGFRN is therefore relevant in inflammatory diseases, reproductive health, cardiovascular function, and potentially in cancer.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Prostaglandin F2 Receptor Negative Regulator (PTGFRN)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 33.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Pro406-Pro662 Tag: N-terminal His tag
expression
Recombinant
purity
> 90%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
PTGFRN
dry ice
No
availability
Shipped within 5-7 working days.
alias
Prostaglandin F2 receptor negative regulator,FPRP,CD315,EWI-F,CD9P-1,SMAP-6,CD9 partner 1,Glu-Trp-Ile EWI motif-containing protein F
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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