Human Prokineticin Receptor 2 (PROKR2) ELISA Kit

Name: Human Prokineticin Receptor 2 (PROKR2) ELISA Kit
Brand: Abbexa
SKU: abx252987
Price: 546 EUR
Availability: OnlineOnly

Este producto es parte de PROKR - Prokineticin Receptor

Pida mas información

935106861

info@markelab.com

Precio

546€ (96 tests)

Elisa kits for PROKR2

proveedor

Abbexa

reference

abx252987

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Prokineticin Receptor 2 (PROKR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Prokineticin Receptor 2 concentrations in tissue homogenates, cell lysates and other biological fluids.

Background

PROKR2, another G protein-coupled receptor for prokineticins, shares functional overlap with PROKR1 but has distinct tissue distribution and physiological roles. It is highly expressed in the central nervous system, particularly in the hypothalamus and olfactory bulb, where it regulates circadian rhythms, neurogenesis, and reproductive function. PROKR2 couples to Gq and Gi/o proteins, stimulating phospholipase C (PLC) and MAPK pathways to regulate neuronal signaling, calcium homeostasis, and cellular responses. PROKR2 is crucial for hypothalamic-pituitary-gonadal axis function, influencing puberty onset and fertility. Mutations in PROKR2 are associated with Kallmann syndrome, characterized by delayed puberty and anosmia (loss of smell). PROKR2 also plays a role in thermoregulation, stress responses, and inflammation. Dysregulation of PROKR2 signaling contributes to reproductive disorders, sleep disturbances, and neuroinflammatory diseases. Targeting PROKR2 holds therapeutic promise for conditions such as infertility, sleep regulation disorders, and neurodevelopmental syndromes.

Características del producto

immunogen target

Prokineticin Receptor 2 (PROKR2)

reactivity

Human

test range

0.312 ng/ml - 20 ng/ml

sensitivity

0.19 ng/ml

assay type

Sandwich

assay data

Quantitative

form

Lyophilized

detection method

Colorimetric

sample type

Tissue homogenates, cell lysates and other biological fluids.

size 1

96 tests

size 2

5 × 96 tests

size 3

10 × 96 tests

alias

PROKR2,GPR73b,VEGFR-2,GPR73a,GPRg2,I5E

storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

or code

PROKR2

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/Q8NFJ6

note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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Prokineticin Receptor 2 (PROKR2) Antibody

proveedor

Abbexa

reference

abx002155

Tested Applications

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

PROKR2 Antibody is a Rabbit Polyclonal antibody against PROKR2.

312€ (60 µl)