Human Progranulin ELISA
520€ (96 det.)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human Progranulin ELISA
Category
ELISA Kits
Provider
Mediagnost
Reference
E103
Tested Applications
Elisa
Description
The Mediagnost Progranulin ELISA is an assay with good reproducibility that detects progranulin and not granulins with high specificity in human Serum and Plasma Samples for research use.
Descripción
Human Progranulina Elisa Kit de Mediagnost es un ensayo con buena reproducibilidad que detecta progranulina y no granulinas con alta especificidad en muestras de suero y plasma humanos para uso en investigación.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Assay Data | Reference Material: recombinant progranulin Incubation Period: 2h Calibrator: recombinant progranulin Controls: 2 controls lyophilised |
| Assay Type | Sandwich |
| Test Range | 0.018 – 103 µg/L |
| Sensitivity | 0.018 µg/L |
| Recommended Dilution | 1:41 |
| Origin | Antibody: Mouse |
| Size 1 | 96 det. |
| Tested Applications | Elisa |
| Sample Type | EDTA / heparin / citrate plasma |
| Availability | 3-5 days. |
| Storage | Shelf life: between 1 and 2 years. Inquire about availability All reagents are stable until the indicated expiry, if stored unopened and protected from sunlight at 2 – 8°C |
| Alias | GEP,FTD2,GP88 |
| Background | Elisa Kits for: GRN |
| Status | RUO |
| Note | Intra/Interassay Variance [%]<10 |
Background
Progranulin is also known as Granulin Epithelin Precursor, Proepithelin or Acrogranin. It is a 68.5 kDa protein, consisting of 593 amino acids (inclusive Signalpeptid), which appears in vivo in strongly glycosylated form and therefore has a size of approximately 90 kDa. Progranulin has seven conserved domains, which are separated by linker sequences. By means of proteolytic cleavage, catalyzed by serine proteases like e.g. elastase, 6-25 kDa large fragments result, that are called Granulines or Epithelines. Progranulin is expressed and secreted in particular in strongly proliferating tissues such as adenoid tissue, spleen, skin epithelium, gastrointestinal mucous membranes, haematopoietic cells and in tumor cells. Until now no specific receptors, which would obtain the effect of Progranulin or the Granulines are known . Progranulin seems to be a factor, which affects the wound healing positively. In case of skin lesions the expression is increased in ceratinocytes, in macrophages and in neutrophile cells. Progranulin affects the wound healing indirectly by activation of macrophages and stimulation of angiogenesis in the damaged tissue.
Productos relacionados
Human Chemerin ELISA
Measurement of human Chemerin in human serum and plasma samples. For research use only. Not for use in diagnostic proced…
Ver producto Human Vaspin ELISA
Mediagnost ELISA for quantitative measurement of Vaspin in human serum is based on polyclonal rabbit antisera raised by …
Ver producto Functional Leptin Elisa
bioLEP ELISA a test for the measurement of biologically active leptinHere, the measurement is not based on two specific …
Ver producto