Human Pregnancy Zone Protein (PZP) CLIA Kit
845€ (96 tests)
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name
Human Pregnancy Zone Protein (PZP) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx495159
tested applications
CLIA
Description
Human Pregnancy Zone Protein (PZP) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Pregnancy Zone Protein (PZP) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.118 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma, tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | CPAMD6,pregnancy zone protein,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6 |
| Background | CLIA Kits PZP |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PZP alpha-2-macroglobulin like (PZP) is a protein that shares structural similarities with alpha-2-macroglobulin, a major inhibitor of proteases in the blood, and functions in regulating immune responses and tissue repair PZP is involved in inhibiting a wide range of proteases, including those involved in inflammation and coagulation, thereby preventing tissue damage caused by excessive protease activity It is expressed in various tissues, including the liver and brain, and has been shown to modulate immune cell activation and inflammatory processes PZP’s role in protease inhibition also extends to its involvement in preventing excessive tissue degradation during injury and infection, contributing to wound healing and tissue remodeling Dysregulation of PZP expression has been linked to inflammatory diseases, including autoimmune conditions, where its altered levels can exacerbate inflammation and tissue damage Furthermore, PZP has been implicated in cancer, where it may influence tumor progression by regulating protease activity within the tumor microenvironment Studies suggest that PZP may also have neuroprotective effects, particularly in diseases like Alzheimer’s, where it modulates protease activity in the brain to reduce neuronal damage
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