Rat Pregnancy Zone Protein (PZP) Protein
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935106861
info@markelab.com
Precio
247€ (10 µg)
Protein PZP
proveedor
Abbexareference
abx068660Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Pregnancy Zone Protein (PZP) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Background
PZP alpha-2-macroglobulin like (PZP) is a protein that shares structural similarities with alpha-2-macroglobulin, a major inhibitor of proteases in the blood, and functions in regulating immune responses and tissue repair PZP is involved in inhibiting a wide range of proteases, including those involved in inflammation and coagulation, thereby preventing tissue damage caused by excessive protease activity It is expressed in various tissues, including the liver and brain, and has been shown to modulate immune cell activation and inflammatory processes PZP’s role in protease inhibition also extends to its involvement in preventing excessive tissue degradation during injury and infection, contributing to wound healing and tissue remodeling Dysregulation of PZP expression has been linked to inflammatory diseases, including autoimmune conditions, where its altered levels can exacerbate inflammation and tissue damage Furthermore, PZP has been implicated in cancer, where it may influence tumor progression by regulating protease activity within the tumor microenvironment Studies suggest that PZP may also have neuroprotective effects, particularly in diseases like Alzheimer’s, where it modulates protease activity in the brain to reduce neuronal damage
Características del producto
category
Proteins and Peptides
origin
Rat
host
E. coli
immunogen target
Pregnancy Zone Protein (PZP)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 53.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu1251-Ala1500 Tag: N-terminal His tag and GST tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
PZP
dry ice
No
availability
Shipped within 5-12 working days.
alias
CPAMD6,pregnancy zone protein,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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