Human Pregnancy-Specific Beta-1-Glycoprotein 1 (PSG1) Protein
377€ (10 µg)
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Name
Human Pregnancy-Specific Beta-1-Glycoprotein 1 (PSG1) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx690279
Tested Applications
SDS-PAGE
Description
Pregnancy-Specific Beta-1-Glycoprotein 1 (PSG1) protein is a recombinant Human protein expressed in HEK293 cells.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Pregnancy-Specific Beta-1-Glycoprotein 1 (PSG1) |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Gln35-Pro419 Tag: C-terminal 6 His tag |
| Origin | Human |
| Observed MW | Calculated MW: 44.5 kDa Observed MW (SDS-PAGE): 68 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Purification | 0.2 µm filtered prior to lyophilization. |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM PBS,150 mM NaCl,pH 7.4, containing 5%-8% Trehalose, Mannitol and 0.01% Tween 80. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | P11464 |
| Gene ID | 5669 |
| OMIM | 176390 |
| Alias | SP1, B1G1,PBG1,CD66f,PSBG1,PSG95,PSGGA,DHFRP2,PSBG-1,PSGIIA,FL-NCA-1/2,PS-beta-C/D,PS-beta-G-1,Fetal liver non-specific cross-reactive antigen 1/2,Pregnancy-specific beta-1 glycoprotein C/D,Pregnancy-specific beta-1-glycoprotein 1 |
| Background | Protein PSG1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in sterile H2O to prepare a stock solution of concentration 0.25 mg/ml. Do not vortex. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Background
Pregnancy-specific beta-1-glycoprotein 1 (PSG1) is part of the pregnancy-specific glycoprotein (PSG) family, which belongs to the immunoglobulin (Ig) superfamily. These glycoproteins are encoded by a group of genes clustered on chromosome 19q13.2. PSG1 is the most abundantly expressed member of the PSG family during pregnancy and plays a crucial role in modulating the maternal immune system to ensure successful pregnancy outcomes. The PSG proteins are primarily produced by the syncytiotrophoblasts of the placenta and released into maternal circulation, where their levels rise significantly during pregnancy. They are considered placental hormones with immunomodulatory and angiogenic properties that help maintain the immunological tolerance of the fetus and support fetal development. PSG1, in particular, has been studied for its involvement in the regulation of immune tolerance, inhibition of inflammatory responses, and promotion of vascularization at the maternal-fetal interface. It is believed to have a key role in creating a favorable environment for fetal growth by modulating maternal immune responses and enhancing placental vascular development.
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