Human PHD finger protein 21B (PHF21B) ELISA Kit

Name: Human PHD finger protein 21B (PHF21B) ELISA Kit
Brand: Abbexa
SKU: abx538475
Price: 715 EUR
Availability: OnlineOnly

Este producto es parte de PHF - PHD finger protein

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for PHF21B

proveedor

Abbexa

reference

abx538475

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human PHD finger protein 21B (PHF21B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human PHD finger protein 21B (PHF21B) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.

Background

PHF21B is a chromatin-binding protein containing a PHD domain, which recognizes and interacts with methylated histones to regulate transcriptional activation or repression. It is involved in chromatin remodeling and modulating gene expression programs linked to cellular proliferation, differentiation, and tumor suppression. PHF21B is expressed in epithelial tissues and immune cells, where it controls pathways involved in cell cycle progression and immune responses. Emerging evidence suggests that PHF21B plays a role in tumor suppression by stabilizing chromatin architecture and regulating oncogene expression. Dysregulation of PHF21B has been implicated in cancers, including breast and colorectal cancer, where its loss of function leads to uncontrolled cell proliferation and genomic instability. Functional studies demonstrate defects in transcriptional repression, impaired chromatin organization, and increased oncogenic signaling, underscoring its role as a critical regulator of epigenetic control and tumor suppression.

Características del producto

immunogen target

PHD finger protein 21B (PHF21B)

reactivity

Human

test range

0.156 ng/ml - 10 ng/ml

assay data

Quantitative

form

Lyophilized

detection method

Colorimetric

sample type

Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.

size 1

96 tests

alias

PHF21B,KIAA1661,BHC80L,PHF4

storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

or code

PHF21B

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/Q96EK2

note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Quizá le pueda interesar

PHD Finger Protein 21B (PHF21B) Antibody

proveedor

Abbexa

reference

abx006556

Tested Applications

ELISA, WB

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

PHF21B Antibody is a Rabbit Polyclonal Antibody against PHF21B.

195€ (20 µl)