Human PHD finger protein 20-like protein 1 (PHF20L1) ELISA Kit

Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for PHF20L1
proveedor
Abbexareference
abx385269Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human PHD finger protein 20-like protein 1 (PHF20L1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human PHF20L1 concentrations in serum, plasma and other biological fluids.
Background
PHF20L1 is a chromatin-binding protein with a PHD finger domain that recognizes methylated histones, particularly H3K4me3, and contributes to transcriptional regulation and chromatin organization. It functions as a transcriptional co-activator or repressor depending on the cellular context and modulates gene expression programs during development and proliferation. PHF20L1 is associated with the regulation of pluripotency, differentiation, and DNA repair, where it stabilizes chromatin architecture and facilitates the recruitment of histone-modifying complexes. It is widely expressed in proliferative and stem cell-rich tissues, playing roles in maintaining genomic stability and epigenetic regulation. Dysregulation of PHF20L1 has been implicated in cancers and neurodevelopmental disorders due to impaired gene regulation and histone recognition. Knockdown studies reveal defects in gene expression, reduced chromatin stability, and impaired cellular differentiation, underscoring its role in transcriptional control and epigenetic regulation.
Características del producto
category
ELISA Kits
immunogen target
PHD finger protein 20-like protein 1 (PHF20L1)
reactivity
Human
test range
0.313 ng/ml - 20 ng/ml
sensitivity
< 0.188 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma and other biological fluids.
size 1
96 tests
alias
PHF20L1,CGI-72, CGI-72,TDRD20B,URLC1
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
PHF20L1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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