Human PHD finger protein 20-like protein 1 (PHF20L1) ELISA Kit
715€ (96 tests)
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name
Human PHD finger protein 20-like protein 1 (PHF20L1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385269
tested applications
ELISA
Description
Human PHD finger protein 20-like protein 1 (PHF20L1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human PHF20L1 concentrations in serum, plasma and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | PHD finger protein 20-like protein 1 (PHF20L1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.188 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | A8MW92 |
| Gene ID | 51105 |
| Alias | PHF20L1,CGI-72, CGI-72,TDRD20B,URLC1 |
| Background | Elisa kits for PHF20L1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PHF20L1 is a chromatin-binding protein with a PHD finger domain that recognizes methylated histones, particularly H3K4me3, and contributes to transcriptional regulation and chromatin organization. It functions as a transcriptional co-activator or repressor depending on the cellular context and modulates gene expression programs during development and proliferation. PHF20L1 is associated with the regulation of pluripotency, differentiation, and DNA repair, where it stabilizes chromatin architecture and facilitates the recruitment of histone-modifying complexes. It is widely expressed in proliferative and stem cell-rich tissues, playing roles in maintaining genomic stability and epigenetic regulation. Dysregulation of PHF20L1 has been implicated in cancers and neurodevelopmental disorders due to impaired gene regulation and histone recognition. Knockdown studies reveal defects in gene expression, reduced chromatin stability, and impaired cellular differentiation, underscoring its role in transcriptional control and epigenetic regulation.
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