Human P2Y Purinoceptor 8 (P2RY8) ELISA Kit
715€ (96 tests)
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name
Human P2Y Purinoceptor 8 (P2RY8) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx537467
tested applications
ELISA
Description
Human P2Y purinoceptor 8 (P2RY8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human P2Y purinoceptor 8 (P2RY8) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | P2Y Purinoceptor 8 (P2RY8) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q86VZ1 |
| OMIM | 300525 |
| Alias | P2RY8,P2Y8,P2Y purinoreceptor 8 |
| Background | Elisa kits for P2RY8 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
P2RY8 is an orphan G protein-coupled receptor within the P2Y receptor family, presumed to respond to extracellular nucleotides like ATP and UDP, although its endogenous ligand remains unclear. P2RY8 is expressed predominantly in immune cells, particularly in lymphocytes and germinal centers of lymphoid tissues, where it modulates immune signaling, cell migration, and lymphocyte development. Its role in immune function positions P2RY8 as a critical regulator of adaptive immunity and germinal center reactions. Dysregulation of P2RY8 signaling has been implicated in hematological malignancies, including B-cell lymphomas and acute lymphoblastic leukemia (ALL), where P2RY8 rearrangements are associated with impaired lymphocyte differentiation and tumor progression. The exact signaling mechanisms and downstream pathways of P2RY8 remain under investigation, but it is emerging as a potential biomarker and therapeutic target in immune-related cancers. Understanding P2RY8’s role in lymphocyte biology and cancer could provide novel approaches for targeted immunotherapy and leukemia treatment.
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Human P2Y Purinoceptor 8 (P2RY8) ELISA Kit
Human P2Y purinoceptor 8 (P2RY8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human P2Y purinoceptor 8 (P2RY8) concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver Producto