Human Oxoeicosanoid Receptor 1 (OXER1) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Oxoeicosanoid Receptor 1 (OXER1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx382008
tested applications
ELISA
Description
Human Oxoeicosanoid Receptor 1 (OXER1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human OXER1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Oxoeicosanoid Receptor 1 (OXER1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.094 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8TDS5 |
| Gene ID | 165140 |
| Alias | OXER1,GPCR,GPR170,TG1019,hGPCR48,R527,5-oxo-ETE receptor,oxoeicosanoid (OXE) receptor 1 |
| Background | Elisa kits for OXER1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
OXER1, also known as the 5-oxo-ETE receptor, is a G protein-coupled receptor activated by 5-oxo-eicosatetraenoic acid (5-oxo-ETE), a bioactive lipid derived from arachidonic acid metabolism. OXER1 is expressed primarily in leukocytes, including eosinophils, neutrophils, and macrophages, where it mediates pro-inflammatory and chemotactic responses. Activation of OXER1 triggers pathways such as PI3K/Akt and MAPK, promoting immune cell migration, cytokine production, and oxidative stress responses. OXER1 plays a crucial role in allergic inflammation, asthma, and other eosinophilic diseases, where it contributes to immune cell recruitment to inflamed tissues. In cancer, OXER1 is implicated in tumor progression and metastasis, particularly in prostate and breast cancers, where 5-oxo-ETE signaling enhances cell proliferation and survival. Dysregulation of OXER1 has also been associated with cardiovascular diseases and chronic inflammatory conditions. Given its roles in inflammation and cancer, OXER1 is considered a promising therapeutic target for managing eosinophilic disorders, chronic inflammation, and tumor progression.
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