Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) ELISA Kit

Este producto es parte de NOD - Nucleotide Binding Oligomerization Domain Containing
Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for NOD2

proveedor

Abbexa

reference

abx258642

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Nucleotide Binding Oligomerization Domain Containing Protein 2 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

CARD15, also known as NOD2 (Nucleotide-binding oligomerization domain containing 2), is a member of the NOD-like receptor (NLR) family, which is involved in the innate immune response. CARD15 plays a critical role in detecting bacterial components, such as muramyl dipeptide, which are found in the cell walls of certain bacteria. Upon activation, CARD15 triggers signaling pathways that lead to the activation of NF-κB and MAPK pathways, promoting the production of pro-inflammatory cytokines. This process is crucial for the immune system to respond to bacterial infections. Mutations in CARD15/NOD2 are associated with several diseases, particularly Crohn's disease, a form of inflammatory bowel disease (IBD), highlighting its role in regulating gut immune responses. Disruptions in CARD15 signaling can result in inappropriate immune activation, contributing to chronic inflammation and autoimmune disorders.

Características del producto

category

ELISA Kits


immunogen target

Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.06 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

NOD2, ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1, nucleotide binding oligomerization domain containing 2, BLAUS, YAOS


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

NOD2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

Human NOD2(Nucleotide-binding oligomerization domain-containing protein 2) ELISA Kit

Human NOD2(Nucleotide-binding oligomerization domain-containing protein 2) ELISA Kit

proveedor

FineTest

reference

EH10600

reactivity

human

status

RUO

Precio a consultar

Ver más

Nucleotide Binding Oligomerization Domain Containing 2 (NOD2) Antibody

Nucleotide Binding Oligomerization Domain Containing 2 (NOD2) Antibody

proveedor

Abbexa

reference

abx114240

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Nucleotide-Binding Oligomerization Domain Containing 2 Antibody is a Rabbit Polyclonal antibody against Nucleotide-Bindi...

637€ (100 µl)

Ver más

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) CLIA Kit

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) CLIA Kit

proveedor

Abbexa

reference

abx190892

Tested Applications

CLIA

reactivity

Human

status

RUO

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) Chemiluminescent Immunoassay (CLIA) Kit is a...

845€ (96 tests)

Ver más