Human Nucleoporin 210 kDa / gp210 (NUP210) Protein

Este producto es parte de NUP - nucleoporin
Human Nucleoporin 210 kDa / gp210 (NUP210) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein NUP210

proveedor

Abbexa

reference

abx168223

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human Nucleoporin 210 kDa Protein is a recombinant Human protein expressed in E. coli.


Background

Nucleoporin 210 (NUP210) is a member of the nuclear pore complex that plays a vital role in the regulation of macromolecular trafficking between the nucleus and cytoplasm NUP210 is involved in the structure and assembly of the nuclear pore, where it contributes to the formation of the central pore channel that allows the selective passage of RNA and proteins across the nuclear envelope It also participates in the regulation of cellular processes such as gene expression, cell cycle progression, and DNA repair by ensuring the proper exchange of factors necessary for these processes NUP210 is particularly important during cell division, where it helps maintain nuclear envelope integrity and supports the organization of the mitotic spindle Dysregulation of NUP210 expression has been associated with diseases such as cancer, where defects in nucleocytoplasmic transport contribute to tumor cell survival, resistance to apoptosis, and metastasis Its involvement in cellular signaling, division, and stress responses underscores its critical role in maintaining overall cellular function and stability

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Nucleoporin 210 kDa / gp210 (NUP210)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 21.2 kDa Observed MW (SDS-PAGE): 21 kDa Concentration: Prior to lyophilization: 1000 µg/ml Sequence Fragment: Leu1288-Val1449 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

NUP210


dry ice

No


availability

Shipped within 5-7 working days.


alias

GP210,POM210,nucleoporin 210kDa,Nuclear pore membrane glycoprotein 210


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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