Human Nucleoporin 210 kDa / gp210 (NUP210) Protein
234€ (10 µg)
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name
Human Nucleoporin 210 kDa / gp210 (NUP210) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168223
tested applications
WB, SDS-PAGE
Description
Human Nucleoporin 210 kDa Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Nucleoporin 210 kDa / gp210 (NUP210) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 21.2 kDa Observed MW (SDS-PAGE): 21 kDa Concentration: Prior to lyophilization: 1000 µg/ml Sequence Fragment: Leu1288-Val1449 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8TEM1 |
| Alias | GP210,POM210,nucleoporin 210kDa,Nuclear pore membrane glycoprotein 210 |
| Background | Protein NUP210 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Nucleoporin 210 (NUP210) is a member of the nuclear pore complex that plays a vital role in the regulation of macromolecular trafficking between the nucleus and cytoplasm NUP210 is involved in the structure and assembly of the nuclear pore, where it contributes to the formation of the central pore channel that allows the selective passage of RNA and proteins across the nuclear envelope It also participates in the regulation of cellular processes such as gene expression, cell cycle progression, and DNA repair by ensuring the proper exchange of factors necessary for these processes NUP210 is particularly important during cell division, where it helps maintain nuclear envelope integrity and supports the organization of the mitotic spindle Dysregulation of NUP210 expression has been associated with diseases such as cancer, where defects in nucleocytoplasmic transport contribute to tumor cell survival, resistance to apoptosis, and metastasis Its involvement in cellular signaling, division, and stress responses underscores its critical role in maintaining overall cellular function and stability
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