Human Nucleoporin 210 kDa / gp210 (NUP210) Protein
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935106861
info@markelab.com
Precio
234€ (10 µg)
Protein NUP210
proveedor
Abbexareference
abx168223Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Human Nucleoporin 210 kDa Protein is a recombinant Human protein expressed in E. coli.
Background
Nucleoporin 210 (NUP210) is a member of the nuclear pore complex that plays a vital role in the regulation of macromolecular trafficking between the nucleus and cytoplasm NUP210 is involved in the structure and assembly of the nuclear pore, where it contributes to the formation of the central pore channel that allows the selective passage of RNA and proteins across the nuclear envelope It also participates in the regulation of cellular processes such as gene expression, cell cycle progression, and DNA repair by ensuring the proper exchange of factors necessary for these processes NUP210 is particularly important during cell division, where it helps maintain nuclear envelope integrity and supports the organization of the mitotic spindle Dysregulation of NUP210 expression has been associated with diseases such as cancer, where defects in nucleocytoplasmic transport contribute to tumor cell survival, resistance to apoptosis, and metastasis Its involvement in cellular signaling, division, and stress responses underscores its critical role in maintaining overall cellular function and stability
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Nucleoporin 210 kDa / gp210 (NUP210)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 21.2 kDa Observed MW (SDS-PAGE): 21 kDa Concentration: Prior to lyophilization: 1000 µg/ml Sequence Fragment: Leu1288-Val1449 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
NUP210
dry ice
No
availability
Shipped within 5-7 working days.
alias
GP210,POM210,nucleoporin 210kDa,Nuclear pore membrane glycoprotein 210
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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