Human NTRK3(Neurotrophic Tyrosine Kinase Receptor Type 3) ELISA Kit

Este producto es parte de NTRK - neurotrophic receptor tyrosine kinase
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935106861
info@markelab.com
name
Human NTRK3(Neurotrophic Tyrosine Kinase Receptor Type 3) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH3448

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Data sheet

Product specifications

CategoryELISA Kits
Reactivityhuman
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich ELISA, Double Antibody
Test Range3.125-200ng/ml
Size 196T
Sample TypeSerum,Plasma,Tissue homogenates,Other biological fluids
AvailabilityShipped within 10-14 working days.
Storage2-8 °C for 6 months
UniProt IDQ16288
AliasTRKC,GP145-TrkC,gp145(trkC),TrkC tyrosine kinase,Neurotrophic tyrosine kinase receptor type 3,NT-3 growth factor receptor
BackgroundElisa Kits NTRK3
StatusRUO

Neurotrophic receptor tyrosine kinase 3 (NTRK3), also known as TrkC, binds primarily with neurotrophin-3 (NT-3) and is integral to the proper development and function of both the central and peripheral nervous systems. This receptor promotes neuronal survival, axonal growth, and the guidance of neuronal connections during development. Dysfunctions in NTRK3 signaling pathways are linked to developmental disorders, including autism spectrum disorders and some cancers, such as medulloblastomas. Its role in neurodevelopment and oncology continues to be a focus of significant clinical research.

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NTRK3 Antibody is a Rabbit Polyclonal antibody against NTRK3. This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.

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