Human NR1I2 (Nuclear receptor subfamily 1 group I member 2) ELISA Kit
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name
Human NR1I2 (Nuclear receptor subfamily 1 group I member 2) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH1200
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.156-10ng/ml |
| Sensitivity | 0.094ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | O75469 |
| Alias | BXR,PAR,PRR,PXR,SAR,SXR,ONR1,PAR1,PAR2,PARq,Orphan nuclear receptor PAR1,Orphan nuclear receptor PXR,Orphan nuclear receptor PAR1,Orphan nuclear receptor PXR,Pregnane X receptor |
| Background | Elisa kits for NR1I2 |
| Status | RUO |
Nuclear receptor subfamily 1 group I member 2 (NR1I2), also known as the pregnane X receptor (PXR), is a nuclear receptor that regulates the expression of genes involved in drug metabolism, xenobiotic detoxification, and the transport of various substances PXR is activated by a wide range of compounds, including steroids, bile acids, and pharmaceuticals, and it controls the transcription of genes involved in the metabolism and clearance of these substances It is primarily expressed in the liver, intestine, and kidneys, where it helps protect the body from harmful substances by promoting their elimination PXR also regulates the expression of genes involved in bile acid metabolism, lipid homeostasis, and steroid hormone synthesis Dysregulation of PXR has been associated with drug resistance, liver diseases, and conditions related to altered drug metabolism Its role in detoxification and drug metabolism makes PXR a key target in pharmacology, particularly in managing drug interactions and toxicity
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