Human NOD2(Nucleotide-binding oligomerization domain-containing protein 2) ELISA Kit

Este producto es parte de CARD - Caspase recruitment domain-containing protein
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935106861
info@markelab.com
name
Human NOD2(Nucleotide-binding oligomerization domain-containing protein 2) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH10600

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.156-10ng/ml
Size 1
96T
Sample Type
Busacar en las instrucciones
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 6 months
UniProt ID
Q9HC29
Alias
NOD2, ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1, nucleotide binding oligomerization domain containing 2, BLAUS, YAOS
Background
Elisa Kits NOD2
Status
RUO

CARD15, also known as NOD2 (Nucleotide-binding oligomerization domain containing 2), is a member of the NOD-like receptor (NLR) family, which is involved in the innate immune response. CARD15 plays a critical role in detecting bacterial components, such as muramyl dipeptide, which are found in the cell walls of certain bacteria. Upon activation, CARD15 triggers signaling pathways that lead to the activation of NF-κB and MAPK pathways, promoting the production of pro-inflammatory cytokines. This process is crucial for the immune system to respond to bacterial infections. Mutations in CARD15/NOD2 are associated with several diseases, particularly Crohn's disease, a form of inflammatory bowel disease (IBD), highlighting its role in regulating gut immune responses. Disruptions in CARD15 signaling can result in inappropriate immune activation, contributing to chronic inflammation and autoimmune disorders.

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