Human NKG2-D type II integral membrane protein (KLRK1) Protein
234€ (2 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human NKG2-D type II integral membrane protein (KLRK1) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx680087
Tested Applications
SDS-PAGE
Description
Human NKG2-D type II integral membrane protein (KLRK1) Protein is a recombinant protein produced in Sf9, Baculovirus cells.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | NKG2-D type II integral membrane protein (KLRK1) |
| Host | Insect |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| Alias | NKG2-D type II integral membrane protein,KLR,CD314,NKG2D,NKG2-D,NK cell receptor D,NKG2-D-activating NK receptor |
| Background | Protein KLRK1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Killer cell lectin-like receptor K1 (KLRK1), commonly known as NKG2D (natural-killer group 2 member D), is an activating receptor expressed on several immune cell types, primarily natural killer (NK) cells and certain subsets of T cells (e.g., CD8+ cytotoxic T cells and gamma-delta (γδ) T cells). KLRK1 plays a pivotal role in immune surveillance by recognizing and binding stress-induced ligands on infected, transformed, or stressed cells, ultimately promoting their elimination. Unlike other receptors that recognize pathogen-specific molecules, KLRK1 targets cells based on “stress signals” upregulated due to infection, cellular transformation, or other cellular stress. KLRK1 serves as a crucial bridge between the innate and adaptive immune systems, offering an immediate response to transformed cells and facilitating longer-lasting adaptive immunity. This receptor is primarily involved in immune responses to tumors, viral infections, and autoimmune processes, where it mediates cytotoxic responses upon recognizing ligands that signal cellular distress or abnormality.
Productos relacionados
NKG2-D Type II Integral Membrane Protein (KLRK1) Antibody
KLRK1 Antibody is a Rabbit Polyclonal antibody against KLRK1. Natural killer (NK) cells are lymphocytes that can mediate…
Ver producto
NKG2-D Type II Integral Membrane Protein (KLRK1) Antibody
KLRK1 Antibody is a Rabbit Polyclonal against KLRK1.…
Ver producto
NKG2-D Type II Integral Membrane Protein (KLRK1) Antibody
KLRK1 Antibody is a Rabbit Polyclonal against KLRK1.…
Ver producto