Nexilin (NEXN) Antibody

Background

Nexilin, encoded by the NEXN gene, is a crucial protein involved in the maintenance and regulation of the actin cytoskeleton. It was first identified through its interaction with F-actin, an essential component of the cytoskeleton, which is involved in various cellular processes including shape maintenance, motility, and intracellular transport. Nexilin is highly expressed in cardiac muscle cells and skeletal muscle cells, highlighting its importance in the function and integrity of muscle tissues. The protein is essential for normal cardiac function and structural integrity, making it a significant player in cardiac health and disease.