Human Neuropeptides B/W receptor type 2 (NPBWR2) ELISA Kit
715€ (96 tests)
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name
Human Neuropeptides B/W receptor type 2 (NPBWR2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx535653
tested applications
ELISA
Description
Human Neuropeptides B/W receptor type 2 (NPBWR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Neuropeptides B/W receptor type 2 (NPBWR2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Neuropeptides B/W receptor type 2 (NPBWR2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P48146 |
| Gene ID | 2832 |
| OMIM | 600731 |
| Alias | NPBWR2,GPR8,G protein-coupled receptor 8,neuropeptides B/W receptor 2 |
| Background | Elisa kits for NPBWR2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
NPBWR2, also known as GPR8, is a G protein-coupled receptor with high affinity for neuropeptide B (NPB) and neuropeptide W (NPW). Unlike NPBWR1, NPBWR2 expression is more limited to specific regions of the brain and peripheral tissues, particularly in the hypothalamus, thalamus, and spinal cord. NPBWR2 couples to Gi/o proteins, inhibiting adenylate cyclase, reducing cAMP levels, and modulating cellular excitability and neurotransmitter release. NPBWR2 is involved in the regulation of feeding behavior, stress responses, and energy metabolism, similar to NPBWR1. It plays a role in modulating nociception and pain perception, particularly in the spinal cord, where it regulates pain transmission. Dysregulation of NPBWR2 has been associated with metabolic disorders, stress-related conditions, and chronic pain syndromes. NPBWR2 is being explored as a therapeutic target for obesity, mood disorders, and pain management, as it influences energy balance, emotional regulation, and nociceptive pathways. Its selective expression and functional roles make it a promising candidate for targeted therapies in CNS disorders.
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