Human Neuropeptide Y Receptor Y2 (NPY2R) ELISA Kit
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935106861
info@markelab.com
Precio
546€ (96 tests)
Elisa kits for NPY2R
proveedor
Abbexareference
abx252827Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Neuropeptide Y Receptor Y2 (NPY2R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Neuropeptide Y Receptor Y2 (NPY2R) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
NPY2R is a G protein-coupled receptor that binds neuropeptide Y (NPY) and peptide YY (PYY) with high affinity. NPY2R is predominantly expressed in the central nervous system (CNS), particularly in the hypothalamus, hippocampus, and brainstem, as well as in peripheral tissues such as the gastrointestinal tract. It functions as an autoreceptor to inhibit the release of NPY and modulates appetite suppression, energy homeostasis, and gastrointestinal motility. NPY2R couples to Gi/o proteins, reducing adenylate cyclase activity, cAMP levels, and neurotransmitter release. Activation of NPY2R reduces food intake and promotes energy expenditure, making it a key target for anti-obesity therapies. It also plays roles in neuroprotection, stress regulation, and cardiovascular function. Dysregulation of NPY2R signaling is associated with metabolic disorders, anxiety, and inflammatory conditions. NPY2R agonists are being developed to treat obesity by enhancing satiety and energy expenditure, highlighting its role as a critical regulator of feeding behavior and metabolism.
Características del producto
category
ELISA Kits
immunogen target
Neuropeptide Y Receptor Y2 (NPY2R)
reactivity
Human
test range
0.312 ng/ml - 20 ng/ml
sensitivity
0.19 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
NPY2R,NPY2-R,neuropeptide Y receptor type 2,NPY-Y2 receptor
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
NPY2R
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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