Human Neuregulin 1 (NRG1) Protein

Este producto es parte de NRG - neuregulin
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481€ (50 µg)

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935106861
info@markelab.com
name
Human Neuregulin 1 (NRG1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx655784
tested applications
WB, SDS-PAGE

Description

Human Neuregulin 1 (NRG1) Protein (Active) is an Active Recombinant Human protein.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Neuregulin 1 (NRG1)
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 26.0 kDa  Observed MW (SDS-PAGE): 28 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Please enquire.
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 90%
Size 1
50 µg
Size 2
100 µg
Size 3
200 µg
Size 4
500 µg
Size 5
1 mg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
GGF,HGL,HRG,NDF,ARIA,GGF2,HRG1,HRGA,SMDF,MST131,MSTP131,NRG1-IT2,Pro-NRG1,Pro-neuregulin-1 membrane-bound isoform,Acetylcholine receptor-inducing activity,Breast cancer cell differentiation factor p45
Background
Protein NRG1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Neuregulin 1 (NRG1) is a pivotal signaling protein within the neuregulin family, recognized for its extensive roles in mediating cell-cell communication across various tissues, particularly the nervous system, cardiac muscle, and epithelial structures. This protein functions as a ligand for ErbB receptor tyrosine kinases, thereby regulating processes such as neuronal differentiation, synaptic development, and myelination of nerve fibers. In cardiac tissue, NRG1 is indispensable for heart development and plays a role in maintaining the function and repair of adult cardiac cells. Dysregulation of NRG1 signaling pathways has been linked to a range of pathological conditions, including schizophrenia, various types of cancer, and heart disease, underscoring its biological and therapeutic importance.

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