Human Neuregulin 1 (NRG1) Protein
234€ (10 µg)
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Name
Human Neuregulin 1 (NRG1) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx263488
Tested Applications
SDS-PAGE
Description
Neuregulin-1/Heregulin-b2 Protein is a recombinant cytokine.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Neuregulin 1 (NRG1) |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 96% (SDS-PAGE and RP-HPLC) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 1 mg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | Q02297 |
| Alias | GGF,HGL,HRG,NDF,ARIA,GGF2,HRG1,HRGA,SMDF,MST131,MSTP131,NRG1-IT2,Pro-NRG1,Pro-neuregulin-1 membrane-bound isoform,Acetylcholine receptor-inducing activity,Breast cancer cell differentiation factor p45 |
| Background | Protein NRG1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Neuregulin 1 (NRG1) is a pivotal signaling protein within the neuregulin family, recognized for its extensive roles in mediating cell-cell communication across various tissues, particularly the nervous system, cardiac muscle, and epithelial structures. This protein functions as a ligand for ErbB receptor tyrosine kinases, thereby regulating processes such as neuronal differentiation, synaptic development, and myelination of nerve fibers. In cardiac tissue, NRG1 is indispensable for heart development and plays a role in maintaining the function and repair of adult cardiac cells. Dysregulation of NRG1 signaling pathways has been linked to a range of pathological conditions, including schizophrenia, various types of cancer, and heart disease, underscoring its biological and therapeutic importance.
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