Human Netrin receptor UNC5A (UNC5A) ELISA Kit
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits UNC5A
proveedor
Abbexareference
abx384131Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Netrin receptor UNC5A (UNC5A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human UNC5A concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
unc-5 netrin receptor A (UNC5A) functions as a dependence receptor, primarily influencing axonal guidance and neural development in response to netrin-1. It mediates repulsive signals, steering neuronal processes during embryogenesis to ensure correct nervous system wiring. Additionally, UNC5A contributes to tissue morphogenesis by regulating cell adhesion and migration. Its role extends beyond neural development to tumor suppression, as its expression mediates apoptosis in the absence of netrin-1. Aberrant regulation of UNC5A has been associated with cancer progression, where its loss can enable evasion of programmed cell death, leading to unchecked tumor growth and metastasis.
Características del producto
category
ELISA Kits
immunogen target
Netrin receptor UNC5A (UNC5A)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.094 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
UNC5H1,Protein unc-5 homolog 1,Protein unc-5 homolog A,Netrin receptor UNC5A
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
UNC5A
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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