Human Netrin receptor UNC5A (UNC5A) ELISA Kit
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Description
Human Netrin receptor UNC5A (UNC5A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human UNC5A concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Netrin receptor UNC5A (UNC5A) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.094 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q6ZN44 |
| Gene ID | 90249 |
| OMIM | 607869 |
| Alias | UNC5H1,Protein unc-5 homolog 1,Protein unc-5 homolog A,Netrin receptor UNC5A |
| Background | Elisa kits for UNC5A |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
unc-5 netrin receptor A (UNC5A) functions as a dependence receptor, primarily influencing axonal guidance and neural development in response to netrin-1. It mediates repulsive signals, steering neuronal processes during embryogenesis to ensure correct nervous system wiring. Additionally, UNC5A contributes to tissue morphogenesis by regulating cell adhesion and migration. Its role extends beyond neural development to tumor suppression, as its expression mediates apoptosis in the absence of netrin-1. Aberrant regulation of UNC5A has been associated with cancer progression, where its loss can enable evasion of programmed cell death, leading to unchecked tumor growth and metastasis.
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