Human N-arachidonyl glycine receptor (GPR18) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for GPR18
proveedor
Abbexareference
abx525987Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human N-Arachidonyl Glycine Receptor (GPR18) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human N-Arachidonyl Glycine Receptor (GPR18) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
GPR18 is an orphan G protein-coupled receptor implicated in immune regulation, lipid signaling, and cannabinoid-like responses. It is widely expressed in immune cells, the central nervous system, and peripheral tissues. GPR18 is activated by endogenous ligands, such as N-arachidonoylglycine (NAGly), and interacts with cannabinoid-like signaling pathways. GPR18 regulates immune cell migration, particularly in macrophages, microglia, and T cells, where it modulates inflammation and resolution of tissue injury. It has been linked to ocular pressure regulation in the eye, making it a potential target for treating glaucoma. In cancer, GPR18 expression promotes tumor progression, survival, and metastasis, particularly in melanoma and breast cancer, where it enhances cell migration and immune evasion. Dysregulation of GPR18 signaling has also been associated with inflammatory and neurodegenerative diseases. Its involvement in immune homeostasis and cannabinoid-like signaling makes GPR18 a promising target for therapeutic development in inflammation, cancer, and neuroimmune disorders.
Características del producto
category
ELISA Kits
immunogen target
N-Arachidonyl Glycine Receptor (GPR18)
reactivity
Human
test range
78 pg/ml - 5000 pg/ml
sensitivity
< 26 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
GRP18,GPCRW,NAGly receptor,N-arachidonoyol glycine receptor,DRV2,G-Protein Coupled Receptor 18
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
GPR18
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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