GPR18 Antibody (HRP)
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
GPR18 Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx306827
tested applications
ELISA
Description
GPR18 Antibody (HRP) is a Rabbit Polyclonal against GPR18 conjugated to HRP.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | GPR18 |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q14330 |
| Gene ID | 2841 |
| OMIM | 602042 |
| Alias | GRP18,GPCRW,NAGly receptor,N-arachidonoyol glycine receptor,DRV2,G-Protein Coupled Receptor 18 |
| Background | Antibody anti-GPR18 |
| Status | RUO |
Descripción
GPR18 is an orphan G protein-coupled receptor implicated in immune regulation, lipid signaling, and cannabinoid-like responses. It is widely expressed in immune cells, the central nervous system, and peripheral tissues. GPR18 is activated by endogenous ligands, such as N-arachidonoylglycine (NAGly), and interacts with cannabinoid-like signaling pathways. GPR18 regulates immune cell migration, particularly in macrophages, microglia, and T cells, where it modulates inflammation and resolution of tissue injury. It has been linked to ocular pressure regulation in the eye, making it a potential target for treating glaucoma. In cancer, GPR18 expression promotes tumor progression, survival, and metastasis, particularly in melanoma and breast cancer, where it enhances cell migration and immune evasion. Dysregulation of GPR18 signaling has also been associated with inflammatory and neurodegenerative diseases. Its involvement in immune homeostasis and cannabinoid-like signaling makes GPR18 a promising target for therapeutic development in inflammation, cancer, and neuroimmune disorders.
Related Products
G-Protein Coupled Receptor 18 (GPR18) Antibody
Rabbit polyclonal antibody against GPR18 protein. Immunogen region is Internal.
Ver Producto
GPR18 Antibody (HRP)
GPR18 Antibody (HRP) is a Rabbit Polyclonal against GPR18 conjugated to HRP.
Ver Producto
GPR18 Antibody (FITC)
GPR18 Antibody (FITC) is a Rabbit Polyclonal against GPR18 conjugated to FITC.
Ver Producto