Human Myosin Light Chain Kinase 4 (MYLK4) ELISA Kit

Este producto es parte de MYLK - myosin light chain kinase
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Myosin Light Chain Kinase 4 (MYLK4) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx534199
tested applications
ELISA

Description

Human Myosin Light Chain Kinase 4 (MYLK4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Myosin Light Chain Kinase 4 (MYLK4) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetMyosin Light Chain Kinase 4 (MYLK4)
ReactivityHuman
Detection MethodColorimetric
Assay DataQuantitative
Test Range0.156 ng/ml - 10 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeSerum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
AvailabilityShipped within 5-15 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
AliasSgK085,Sugen kinase 85,Myosin light chain kinase family member 4
BackgroundElisa kits for MYLK4
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Myosin Light Chain Kinase 4 (MYLK4) is a member of the myosin light chain kinase (MLCK) family, which are serine/threonine protein kinases that phosphorylate myosin light chains (MLC) to regulate actomyosin contractility and cytoskeletal dynamics. MYLK4, like other MYLK family members, plays a role in cellular processes involving actin-myosin interactions, including cell movement, shape maintenance, and intracellular transport. Structurally, MYLK4 contains kinase domains that share homology with other MLCKs but has notable differences in regulatory regions, including the lack of calmodulin-binding motifs typically found in other family members. This suggests MYLK4 might have a calcium-independent regulation mechanism, distinguishing it from classic MLCKs like MYLK1. MYLK4 is expressed in various tissues, including the skeletal muscle, brain, and reproductive organs, suggesting its involvement in diverse biological functions. Emerging evidence indicates its role in cytoskeletal remodeling, which is critical for processes like neuronal development and muscle maintenance. MYLK4’s expression in non-muscle tissues points to additional, less-defined regulatory roles in cellular signaling pathways.

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