Mouse Myosin Light Chain Kinase 4 (MYLK4) Protein

Product specifications

Proteins and Peptides

Myosin Light Chain Kinase 4 (MYLK4)

E. coli

Mouse

Unconjugated

Molecular Weight: Calculated MW: 33.3 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Ala96-Ser353
Tag: N-terminal His tag and GST tag

Recombinant

> 95%

10 µg

50 µg

100 µg

200 µg

500 µg

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.

WB, SDS-PAGE

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

Shipped within 5-7 working days.

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.

No

Q5SUV5

SgK085,Sugen kinase 85,Myosin light chain kinase family member 4

Protein MYLK4

RUO

This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Myosin Light Chain Kinase 4 (MYLK4) is a member of the myosin light chain kinase (MLCK) family, which are serine/threonine protein kinases that phosphorylate myosin light chains (MLC) to regulate actomyosin contractility and cytoskeletal dynamics. MYLK4, like other MYLK family members, plays a role in cellular processes involving actin-myosin interactions, including cell movement, shape maintenance, and intracellular transport. Structurally, MYLK4 contains kinase domains that share homology with other MLCKs but has notable differences in regulatory regions, including the lack of calmodulin-binding motifs typically found in other family members. This suggests MYLK4 might have a calcium-independent regulation mechanism, distinguishing it from classic MLCKs like MYLK1. MYLK4 is expressed in various tissues, including the skeletal muscle, brain, and reproductive organs, suggesting its involvement in diverse biological functions. Emerging evidence indicates its role in cytoskeletal remodeling, which is critical for processes like neuronal development and muscle maintenance. MYLK4’s expression in non-muscle tissues points to additional, less-defined regulatory roles in cellular signaling pathways.

Related Products

anti- MYLK4 antibody

Ver Producto

Myosin Light Chain Kinase 4 (MYLK4) Antibody

MYLK4 Antibody is a Rabbit Polyclonal antibody against MYLK4.

Ver Producto

Myosin Light Chain Kinase 4 (MYLK4) Antibody

Rabbit Polyclonal against the MYLK4 protein.

Ver Producto