Human Myosin Light Chain Kinase 2 (MYLK2) ELISA Kit
![Human Myosin Light Chain Kinase 2 (MYLK2) ELISA Kit](/_next/image?url=https%3A%2F%2Fwww.abbexa.com%2Fimage%2Fcache%2Fcatalog%2FGraphs%2F29%2Fabx381645%2Fabx381645_Human_Myosin_Light_Chain_Kinase_2_MYLK2_ELISA_Kit_graph-250x250.png&w=3840&q=75)
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits MYLK2
proveedor
Abbexareference
abx381645Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Myosin Light Chain Kinase 2 (MYLK2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human MYLK2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Myosin light chain kinase 2 (MYLK2) is a muscle-specific isoform of myosin light chain kinase predominantly expressed in skeletal muscle tissue. MYLK2 plays a key role in regulating myosin activity during muscle contraction by phosphorylating the regulatory light chains of myosin II, a process critical for force generation and sarcomere function. The kinase activity of MYLK2 is tightly regulated by calcium-calmodulin signaling, ensuring precise control of contractile responses during dynamic skeletal muscle activities such as exercise and locomotion. MYLK2 also contributes to the adaptive remodeling of muscle fibers in response to mechanical stress and physiological demands. Mutations or dysregulation of MYLK2 have been associated with myopathies and muscle weakness, emphasizing its essential role in maintaining muscular integrity and function.
Características del producto
category
ELISA Kits
immunogen target
Myosin Light Chain Kinase 2 (MYLK2)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.07 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
KMLC,MLCK,MLCK2,skMLCK,Myosin light chain kinase 2, skeletal cardiac muscle
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
MYLK2
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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