Human Multidrug Resistance Associated Protein 9 (ABCC12) Protein
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Human ATP Binding Cassette Transporter C12 (ABCC12) Protein is a Recombinant Human protein expressed in E. coli.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Multidrug Resistance Associated Protein 9 (ABCC12) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Please enquire. Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 1 mg |
| Size 2 | 5 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 1-2 months. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96J65 |
| Gene ID | 94160 |
| OMIM | 607041 |
| Alias | MRP9,ATP-binding cassette sub-family C member 12 |
| Background | Protein ABCC12 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ABCC12, a member of the ABCC subfamily, is a membrane-associated transporter protein implicated in multidrug resistance and cellular detoxification processes. Its expression is observed in various tissues, including the testis and breast. Although its exact substrates and biological functions remain under investigation, ABCC12 may contribute to transporting organic anions or xenobiotics. Dysregulation or mutations in ABCC12 have potential links to cancer progression and drug resistance. Further research is essential to elucidate its precise physiological and pathological roles.
Related Products
Human ABCC12(Multidrug resistance-associated protein 9) ELISA Kit
Ver Producto
Multidrug Resistance Associated Protein 9 (ABCC12) Antibody
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.
Ver Producto
Human Multidrug Resistance Associated Protein 9 (ABCC12) ELISA Kit
Human Multidrug Resistance Associated Protein 9 (ABCC12) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Multidrug Resistance Associated Protein 9 (ABCC12) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of ATP Binding Cassette Transporter C12 (ABCC12)
Ver Producto