Human MRGPRX2 (Mas-related G-protein coupled receptor member X2) ELISA Kit

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935106861
info@markelab.com
name
Human MRGPRX2 (Mas-related G-protein coupled receptor member X2) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH14556
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Reactivity | Human |
Detection Method | Colorimetric |
Assay Data | 4 hours |
Assay Type | Sandwich ELISA, Double Antibody |
Test Range | 1.563-100ng/ml |
Sensitivity | 0.938ng/ml |
Size 1 | 96T |
Tested Applications | ELISA |
Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
Availability | Shipped within 10-14 working days. |
Storage | 2-8 °C for 12 months |
UniProt ID | Q96LB1 |
Alias | MRGPRX2,Mrgprb10,MRGX2,MGRG3 |
Background | Elisa kits for MRGPRX2 |
Status | RUO |
MRGPRX2 is another receptor in the MAS-related GPR family, which is involved in immune and sensory functions. It is primarily expressed in mast cells and sensory neurons, where it contributes to the regulation of allergic reactions and inflammatory responses. MRGPRX2 is activated by endogenous peptides, including substance P, and plays a significant role in mediating the release of histamine from mast cells, leading to allergic symptoms such as itching, swelling, and redness. Additionally, MRGPRX2 has been implicated in pain signaling and neurogenic inflammation. This receptor’s involvement in allergic responses and its ability to modulate mast cell activation makes it a key player in conditions such as asthma, rhinitis, and other allergic disorders. Targeting MRGPRX2 with antagonists offers therapeutic potential for treating allergic conditions and managing symptoms related to mast cell activation.
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