Human Microfibrillar Associated Protein 5 (MFAP5) ELISA Kit
715€ (96 tests)
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name
Human Microfibrillar Associated Protein 5 (MFAP5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx250635
tested applications
ELISA
Description
Human Microfibrillar Associated Protein 5 (MFAP5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Microfibrillar Associated Protein 5 (MFAP5) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Microfibrillar Associated Protein 5 (MFAP5) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | AAT9,MP25,MAGP2,MAGP-2,MFAP-5,Microfibril-associated glycoprotein 2 |
| Background | Elisa kits for MFAP5 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Microfibril Associated Protein 5 (MFAP5), also known as MAGP-2, is another extracellular matrix protein associated with microfibrils. MFAP5 is involved in maintaining the structural integrity of elastic fibers and modulating cell-matrix interactions. It plays a significant role in angiogenesis, influencing endothelial cell adhesion, migration, and survival. MFAP5 has been linked to tumor progression and metastasis, particularly in ovarian and other cancers, where it contributes to a pro-tumorigenic microenvironment. Elevated levels of MFAP5 are associated with poor prognosis in cancer due to its role in promoting angiogenesis and remodeling of the extracellular matrix. MFAP5 is also implicated in fibrotic diseases, where it affects tissue stiffness and pathological remodeling.
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May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity(By similarity). Component of the elastin-associated microfibrils(PubMed:8557636).
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