anti- MFAP5 antibody
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Precio
Precio a consultar
Antibody anti-MFAP5
proveedor
FineTestreference
FNab05147Tested Applications
ELISA, WB, IHCreactivity
human,mouse,ratstatus
RUOclonality
polyclonalDescripción
May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity(By similarity). Component of the elastin-associated microfibrils(PubMed:8557636).
Background
Microfibril Associated Protein 5 (MFAP5), also known as MAGP-2, is another extracellular matrix protein associated with microfibrils. MFAP5 is involved in maintaining the structural integrity of elastic fibers and modulating cell-matrix interactions. It plays a significant role in angiogenesis, influencing endothelial cell adhesion, migration, and survival. MFAP5 has been linked to tumor progression and metastasis, particularly in ovarian and other cancers, where it contributes to a pro-tumorigenic microenvironment. Elevated levels of MFAP5 are associated with poor prognosis in cancer due to its role in promoting angiogenesis and remodeling of the extracellular matrix. MFAP5 is also implicated in fibrotic diseases, where it affects tissue stiffness and pathological remodeling.
Características del producto
category
Primary Antibodies
clonality
polyclonal
reactivity
human,mouse,rat
immunogen target
microfibrillar associated protein 5
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
liquid
tested applications
ELISA, WB, IHC
observerd MW
20 kDa
purity
≥95% as determined by SDS-PAGE
purification
Immunogen affinity purified
recommended dilution
WB: 1:1000-1:3000; IHC: 1:200-1:1000
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
or code
MFAP5
alias
AAT9,MP25,MAGP2,MAGP-2,MFAP-5,Microfibril-associated glycoprotein 2
uniprot id
note
This product is for research use only.
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