Human MFAP5 (Microfibrillar-associated protein 5) ELISA Kit
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name
Human MFAP5 (Microfibrillar-associated protein 5) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH1364
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.313-20ng/ml |
| Sensitivity | 0.188ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q13361 |
| Alias | AAT9,MP25,MAGP2,MAGP-2,MFAP-5,Microfibril-associated glycoprotein 2 |
| Background | Elisa kits for MFAP5 |
| Status | RUO |
Microfibril Associated Protein 5 (MFAP5), also known as MAGP-2, is another extracellular matrix protein associated with microfibrils. MFAP5 is involved in maintaining the structural integrity of elastic fibers and modulating cell-matrix interactions. It plays a significant role in angiogenesis, influencing endothelial cell adhesion, migration, and survival. MFAP5 has been linked to tumor progression and metastasis, particularly in ovarian and other cancers, where it contributes to a pro-tumorigenic microenvironment. Elevated levels of MFAP5 are associated with poor prognosis in cancer due to its role in promoting angiogenesis and remodeling of the extracellular matrix. MFAP5 is also implicated in fibrotic diseases, where it affects tissue stiffness and pathological remodeling.
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May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity(By similarity). Component of the elastin-associated microfibrils(PubMed:8557636).
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