Human Microfibrillar Associated Protein 2 (MFAP2) Protein
767€ (50 µg)
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935106861
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name
Human Microfibrillar Associated Protein 2 (MFAP2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx651415
tested applications
WB, SDS-PAGE
Description
Microfibrillar Associated Protein 2 (MFAP2) Protein (Active) is an active protein from Human.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Microfibrillar Associated Protein 2 (MFAP2) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 22.0 kDa Observed MW: 38 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu6-Val162 Tag: N-terminal His tag |
| Purity | > 95% |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 500 µg |
| Size 5 | 1 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P55001 |
| Alias | MAGP,MAGP1,MAGP-1,MFAP-2 |
| Background | Protein MFAP2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Microfibril Associated Protein 2 (MFAP2), also known as MAGP-1, is a component of the extracellular matrix associated with microfibrils. MFAP2 interacts with fibrillin and elastin to contribute to the structural integrity and elastic properties of connective tissues. It plays a role in modulating signaling pathways such as TGF-β and BMP, which are crucial for tissue homeostasis, repair, and development. Dysregulation of MFAP2 has been implicated in connective tissue disorders, including Marfan syndrome and aortic aneurysms, due to its impact on microfibril assembly and extracellular matrix stability. MFAP2 also has emerging roles in angiogenesis and tumor progression, where it influences the extracellular microenvironment and cell signaling.
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